>>39478167Because both cocaine and SSRIs cause build up in naturally produced organic compounds.
The first one binds to dopamine transporters, the second one binds to serotonin reuptake receptors.
The effect is the same as injecting pure catecholamines.
https://en.m.wikipedia.org/wiki/Drug_toleranceBut you are right, actually. Steroids do upregulate their own receptors.
Increasing the amount of T is supranatural for your androgen receptors, but only in the beginning. I wasn't arguing on this, but since it felt like I did, I'll agree to concede on this one. Your body needs to upregulate itself to fully utilize androgens.
That said, your aromatase production also upregulates. Hence, as
>>39477953noted, you get all the E.
The question is: why would it lower itself once you reach enough ARs to utilize all the T?
Estrogen and Testosterone are transcription factors, yes, but only in the uterus.
Once the child is born they become activating factors.
(If you need me to explain transcrition factors and activating factors, then tell me)
Your DNA is female, XX. Your increase in the number of receptors just increases the aromatase production, since T activates aromatase, which turns T into E, which upregulates estrogen receptors, which in turn upregulate CYP19A1 expression.
https://www.sciencedirect.com/science/article/abs/pii/S001664802100232XThe amount of T you have in your body is not natural, unless you downregulate your E production (in other words, if you inhibit its production through hormone blockers).
In conclusion, I think you'd benefit from hormone blockers.
How much, and if my reasoning is true? I don't know.
You trannies should tell me this shit.
